It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

Researchers at University of Tsukuba and their collaborators have conducted a comprehensive analysis of the olfactory ...

CAG repeats can get longer over time as the HD gene is used, like the growing potholes and cracks in an old road. New ...

Revolutions in gene therapy are rapidly changing the landscape of modern medicine. Revolutions in gene therapy are rapidly changing the landscape of modern medicine, forcing society and science alike ...

A novel gene therapy has been found to significantly slow the progression of Huntington’s disease, offering new hope to sufferers of the incurable disorder that destroys brain cells over time.

Gene-set analysis seeks to identify the biological mechanisms underlying groups of genes with shared functions. Large language models (LLMs) have shown promise in generating functional descriptions ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ...

In the complex world of neuroscience, Huntington's disease remains a cruel mystery. It slowly strips away a person’s ability to think and move, yet scientists still don't fully understand why.

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating ...