Pixelgen Technologies Further Expands Asia Presence Through Distribution Agreement with MDxK

Inc., part of DKSH Business Unit Technology, a leader in market expansion services, today announced a distribution agreement to bring Pixelgen's Proxiome Kit to life sciences researchers in South ...
IEEE

Tracking Mobile Users in Wireless Networks via Semi-Supervised Colocalization

Abstract: Recent years have witnessed the growing popularity of sensor and sensor-network technologies, supporting important practical applications. One of the fundamental issues is how to accurately ...
GitHub

Hypothesis Prioritisation in multi-trait Colocalization (HyPrColoc).

Genome-wide association studies (GWAS) have identified thousands of genomic regions affecting complex diseases. The next challenge is to elucidate the causal genes and mechanisms involved. One ...
The Lancet

Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19

aDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China bShanghai ...
The Lancet

Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic ...

kDepartment of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA lDepartment of Medicine and Human Genetics, Division of Gastroenterology, Hepatology and Parenteral Nutrition, ...
GitHub

Colocalization of fine-mapped signals with coloc.susie

These are instructions for running the colocalization workflow assuming you have a fresh Ubuntu 22 install on a GCP VM. Here we run the workflow locally on the VM. We run all FinnGen fine-mapped ...
eLife

Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations

Many GWAS studies have been done to understand the genetic contributions to bone density, but very few have managed to pinpoint the gene affected by a polymorphism that caused an observed difference.
eLife

Determination of oligomeric states of proteins via dual-color colocalization with single molecule localization microscopy

The oligomeric state of plasma membrane proteins is the result of the interactions between individual subunits and an important determinant of their function. Most approaches used to address this ...