Blocking a key gene regulator may restore immune response in cancer therapy

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target ...
New Scientist

Human-plant hybrid cells reveal truth about dark DNA in our genome

It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...
Interesting Engineering

AI uncovers 360,000 DNA knots that quietly shape how genes turn on and off

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.
HDBuzz

A road less traveled: how making less huntingtin can alter somatic instability and may delay symptoms

CAG repeats can get longer over time as the HD gene is used, like the growing potholes and cracks in an old road. New ...
hdbuzz.net

A tug-of-war at the DNA: how Huntington’s repeats grow and shrink

Ever since large genetic studies in Huntington’s disease (HD) revealed that the longer the CAG expansion, the earlier symptoms appear, we’ve known that repeat length matters. Recent work has ...
Goodnet

Huntington’s Disease Successfully Treated in a World First

The results of recent clinical trials of gene therapy uniQure in the USA and the UK, and detailed in a uniQure media release, prior to publication in a peer-reviewed journal, show a world first: the ...
Forbes

Gene Editing Or Gene Silencing: The Therapies Poised To Transform Medicine

Revolutions in gene therapy are rapidly changing the landscape of modern medicine. Revolutions in gene therapy are rapidly changing the landscape of modern medicine, forcing society and science alike ...