If these two things happen, the 49ers would finish 13-4 and win the NFC West over a 13-4 Rams team based on the division record tiebreaker. If the Seahawks also finish 13-4 in this scenario, the 49ers would have swept them, so they'd win any tiebreaker with Seattle. At 7-to-1 odds to win the NFC West, the 49ers feel like a steal.

The Seahawks have won as many games as they did a year ago, as have the reigning NFC West champion. An eventual rematch with the Rams is the key to the season.

Facing Philip Rivers and the Colts, the Seahawks have a chance to reach 99% playoff odds, and likely cement, or raise, their 32% chance of clinching the NFC's No.1 seed from the Rams.

Ryan Clark unloaded on the Indianapolis Colts over the news that they will play Philip Rivers against the Seattle Seahawks.

According to Tom Pelissero at NFL.com, the Seahawks lead the league in EPA/play defensively since the Week 8 bye, and they rank eighth offensively.

Indianapolis is a good team, but its lack of stability at the quarterback position will continue to hurt them Sunday in Seattle. Unless either Riley or Rivers can pull off the unthinkable, the Colts will drop their fourth straight game while the Seahawks will pick up their fourth straight win. Pick: Seahawks -13.5, Under 40.5

Is De'Von Achane about to run circles around another defense? Which Rams receiver will catch four touchdown passes from Matthew Stafford? Our analysts provide bold predictions for Week 15 of the 2025 NFL season.

See an updated list of injuries, with active and inactive players for the Seattle Seahawks vs. Indianapolis Colts NFL Week 15 game.