The genetic mutation that causes Huntington’s disease (HD) – a devastating brain disease that disrupts mobility and diminishes cognitive ability – may also enhance early brain development and play a ...
Huntington’s Disease organoids (right) exhibit almost no neural progenitors (red) and also show defects in cellular polarity (yelllow). These defects have been described in the literature in human ...
A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease? They found that HTT ...
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